Part:BBa_K3117040:Design

constant region 1 (CH1) of an antibody

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal AgeI site found at 105
  
• 1000
  COMPATIBLE WITH RFC[1000]

Design Notes

For the creation of Fabs, CH1 was fused to a variable single chain fragment and the Igk light chain. The disulfid bonds that connects the two Fab fragments can be used to chemically conjugate two Fabs.

Source

CH1 originates from genomic DNA.